Compra Lipitor Toscana
Valutazione 4.7 sulla base di 112 voti.
Body as a whole: No cases of rhabdomyolysis Toscana reported. Diabetes Compra reported as an adverse reaction in 144 subjects 6. The incidence of non-fatal hemorrhagic strokes was significantly greater in the atorvastatin group Lipitor non-fatal hemorrhagic strokes as compared to the placebo group 16 non-fatal hemorrhagic strokes.
Che cosa è Lipitor?
There were no significant differences between the treatment groups for all-cause mortality: Adverse reactions associated with LIPITOR therapy reported since market introduction, that are not listed above, regardless of causality assessment, include the following: There have been rare reports of immune-mediated necrotizing myopathy associated with statin use [see Warnings and Precautions 5. There have been rare postmarketing reports of cognitive impairment e. These cognitive issues have been reported for all statins. The reports are generally nonserious, and reversible upon statin discontinuation, with Compra times to symptom onset 1 day Toscana years and symptom resolution median of 3 weeks.
The extent of interaction and potentiation of effects depend on the variability of effect on CYP 3A4, Compra Lipitor Toscana. Patients taking digoxin should Lipitor monitored appropriately.
The estimated background risk of major birth defects and miscarriage for the indicated population is unknown, Compra Lipitor Toscana. Data Human Data Limited published data on Compra calcium from observational studies, meta-analyses and case reports have not shown an increased risk of major congenital malformations or miscarriage. Rare reports of Toscana anomalies have been received Lipitor intrauterine exposure to other HMG-CoA reductase inhibitors.
Animal Data Atorvastatin crosses the rat placenta and reaches a level in fetal liver equivalent to that of maternal plasma, Compra Lipitor Toscana. Because of the potential for Compra adverse reactions in a breastfed infant, advise women that breastfeeding is not recommended during treatment with LIPITOR.
A Lipitor clinical trial of 6 months duration in 187 boys and postmenarchal girls, 10 years to 17 years of age. Toscana treated with 10 mg or 20 mg daily LIPITOR had an adverse reaction profile generally similar to that of patients treated with placebo. The safety and efficacy of LIPITOR in lowering LDL-C appeared generally consistent with that observed for adult patients, despite limitations of the uncontrolled study design Advise postmenarchal girls of contraception recommendations, if appropriate for the patient [see Use in Specific Populations 8.
¿Cuál es la información más importante que debo saber sobre atorvastatin?
The long-term efficacy of Compra therapy initiated in childhood to reduce morbidity and mortality in adulthood has not been established. In Lipitor event of an overdose, the patient should be treated symptomatically, and Toscana measures instituted as required. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis.
Atorvastatin calcium is a white to off-white crystalline powder that is insoluble in aqueous solutions of pH 4 and below.
Atorvastatin calcium is very slightly soluble in distilled water, pH 7. The liver is the primary site of action and the principal site of cholesterol synthesis and LDL clearance, Compra Lipitor Toscana. In animals, the ortho-hydroxy metabolite undergoes further glucuronidation. Cmax and AUC are approximately 16-fold and 11-fold increased, respectively, in patients with Childs-Pugh B disease. Atorvastatin is also identified as a substrate of the efflux transporter BCRP, which may limit the intestinal absorption and biliary clearance of atorvastatin.